how long does omicron last in vaccinated people how long does omicron last in vaccinated people

The XBB.1.16 Omicron subvariant is increasing, with anecdotal reports that it may be causing some unusual symptoms like pink eye. The bivalent vaccines also broaden the immune response, which is expected to improve protection against future variants and extend the strength of protection. Young people are more likely to die of heart attacks post-COVID, study finds. A new omicron subvariant, XBB.1.16, is spreading in the United States, and some doctors are reporting that it may be causing unusual symptoms. Overall, experts believe that the most robust protection is through vaccination and boosters, which means it's important "to not rely on natural immunity to be highly protective for Omicron," MacDonald said. UC Davis Health is offering bivalent boosters for anyone at any of our, . - April 24, 2023. If you have a medical emergency, call 911 and notify them of your COVID-19 symptoms. The new Omicron subvariant, known as BA.2.12.1 by researchers currently chronicling its spread, has been purported to be 25% more contagious than earlier Omicron strains and has led to an uptick in breakthrough COVID-19 cases. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. By Carla Delgado WiseJ.Covid-19: Omicron infection is poor booster to immunity, study finds. How Often Should People Get COVID Boosters - Scientific American (2023) By Dr Frank Yap, M.D. "It looks very much like XBB.1.5, which is the dominant variant in the U.S. and has been the dominant variant here and in many other countries for some time," Dr. Andy Pekosz, a virologist at Johns Hopkins University, tells TODAY.com. Omicron and its iterations likely aren't going away anytime soon, and you may still contract the virus (although likely a milder version) even if you have been vaccinated or boosted, or have had a previous case of COVID-19. Zee Krstic is a health editor for Good Housekeeping, where he covers health and nutrition news, decodes diet and fitness trends and reviews the best products in the wellness aisle. JAMA Netw Open. A major concern for those affected by a breakthrough COVID-19 illness, then, is how long recovery will take. Because of this, it may be able to "outrun" or outcompete other variants, he adds. Caroline Kee is a health reporter at TODAY based in New York City. For an optimal experience visit our site on another browser. The FDA has authorized a second updated COVID booster for older people and immunocompromised individuals. Here are all known COVID-19 symptoms associated with the current Omicron subvariant wave, according to the CDC: Healthcare experts have established in the past that SARS-CoV-2 variants may trigger one set of symptoms more commonly than others and the same is true for the current viral Omicron subvariant, BA.2.12.1. She is most passionate about stories that cover real issues and spark change. The natural immunity from a COVID-19 infection with Omicron likely lasts about four to six months, similar to other variants. This means that some common symptoms, like cough, fatigue, body aches, and shortness of breath, among others, can linger beyond 2 weeks," Boden-Albala says. The CDC has some pretty specific rules centered on isolation time with COVID-19, regardless of the variant: If you test positive, regardless of vaccination status, you should isolate at home for five full days. Those infected with COVID-19 sometimes experience change in or loss of taste and smell, which is less common with the flu. This includes an increased risk for: Read more: 9 things we've learned about long COVID so far. If you've been exposed to someone with the virus or have COVID-19 symptoms and are waiting for a test or your results, stay home and isolate from others. This is where booster vaccines often come in, as staying up-to-date on COVID-19 vaccinations including signing up for a fourth shot if you're over the age of 50 is crucial to avoid future spread of other SARS-CoV-2 variants. "The vaccines are safe, they're effective, and theyre underutilized," Schaffner adds. Vitale J, Mumoli N, Clerici P, et al. Isolation and precautions for people with COVID-19, Omicron infection enhances Delta antibody immunity in vaccinated persons, Immune boosting by B.1.1.529(Omicron) depends on previous SARS-CoV-2 exposure, Covid-19: Omicron infection is poor booster to immunity, study finds, Prior Omicron infection protects against BA.4 and BA.5 variants. Given how infectious BA.5 is, its important for everyone to take all precautions, including getting vaccinated and wearing a well-fitted face mask (N95 or KN95, if possible). Breakthrough infections are in people who have been vaccinated or previously had COVID. Thus, wearing an excellent-fitting, high-efficacy mask continuously whenever at potential risk remains important for prevention.. Most. How Long Does An Omicron Infection Last in the Body? What about the bivalent booster? But a few existing studies suggest people are unlikely to remain infectious after 10 days. 2021;181(10):14071408. Why Doesn't the U.S. Account for Natural Immunity? After the five-day mark, people may start easing up on isolating. What to Know About Omicron BA.5 Reinfections, What You Need to Know About the Updated COVID-19 Boosters. Breakthrough infections, too, are expected to occur with Omicron and its subvariants. The WHO said it is "carefully monitoring" for signs of increased severity in a risk assessment of XBB.1.16. . At-home COVID tests, also known as rapid antigen tests, are useful because they provide quick results. Instead of testing right away, you could monitor for COVID-19 symptoms and get tested if any develop. Telehealth video visits and Express Care are also available. However, people infected with, If your illness gets worse, youll want to know so you can take advantage of. What are the differences between flu symptoms and omicron symptoms? Why Are There So Many Omicron SubvariantsAnd What Can They Tell Us About the Future of the Pandemic? Some people are still at risk for severe disease, hospitalization, or even death. The incubation period of a virus is how long it takes from being infected with the virus until symptoms start to show up. It also looks like vaccination plus previous infection work together to boost immunity from an Omicron infection. What Is Croup and Its Link to COVID-19 in Children? Because of Omicron's shortened incubation period, those who are infected will begin to show symptoms sooner, if they're symptomatic. "One of those options is monoclonal antibody treatment; these drugs are administered through an IV that work like the body's natural antibodies in fighting off disease.". It's . You may be able to find the same content in another format, or you may be able to find more information, at their web site. Omicron infection enhances Delta antibody immunity in vaccinated persons. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. Nearly one in. Learn more about the difference between quarantine and isolation. MMWR Morb Mortal Wkly Rep. 2021;70. doi:10.15585/mmwr.mm7050e1. You can schedule your bivalent vaccine through, (non-patients without a login will have to create an account) or by calling, . Unvaccinated bearing the brunt of the surge. Tests can be purchased without a prescription and are available at pharmacies and stores. Flu usually begins with a cough, whereas COVID-19 most often starts with a fever. It's during that time when people typically have the highest viral load and are most contagious. Influenza (flu) and COVID-19 are both contagious respiratory illnesses, and they have similar symptoms. How Long Does Immunity From Omicron Last? This means the variant is better at dodging antibodies the body has produced to help fight off the virus, TODAY.com previously reported. Id recommend getting the second booster at about five months after the first booster.. Since very early in the pandemic, we've known that older individuals are among those most susceptible to severe outcomes from Covid-19. "However, everywhere we see 1.16, it does seem to start increasing at a pretty fast rate, says Pekosz, adding that it is "something to watch.". This action includes authorizing the current bivalent vaccines (original and omicron BA.4/BA.5 strains) to be used for all doses administered to individuals 6 months of age and older, including . Those with COVID-19 typically develop symptoms 3-4 days after being infected. Individuals ages 6 years and older who have already received an updated mRNA vaccine do not need to take any action unless they are 65 years or older or immunocompromised. It (also) has at least two mutations in the spike proteins that will probably cause it to evade some amount of vaccine-induced immunity or immunity-induced by infection with XBB.1.5, says Pekosz. Its ability to cause severe disease appears to be similar to prior omicron variants, Dr. Albert Ko, an infectious disease physician and professor at Yale School of Public Health, tells TODAY.com. This is why current CDC quarantine rules have been adapted in recent months, Dr. Wright explains. Will Omicron Show Up On Rapid COVID Tests? In that case, here's what a typical timeline of an Omicron infection looks like, from exposure to immunity. Are COVID-19 vaccines effective in protecting against omicron BA.5? 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. A majority of vaccinated Americans are now treating their symptoms while in recovery sequestered at home, Boden-Albala adds but not every recovery process is the same. However, reinfection can still occur earlier than that. Even with vaccination, no infection. "They're starting to do this the way we do routinely with our influenza vaccine, which we update on an annual basis," says Schaffner, adding that annual boosters could become a norm in the future, especially for higher-risk groups. Coelho DH, Reiter ER, French E, Costanzo RM. The message from health experts remains that everyone should be vaccinated against COVID-19. Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-COV-2 during periods of Omicron and Delta variant dominance: A prospective observational study from the ZOE COVID Study. A person is generally contagious a day or two before symptoms begin and at least two or three days after. Experts assume that the elderly and those with underlying conditions will have less robust immune protection from an Omicron infection, just as they did to prior variants and to vaccines, Stanley H. Weiss, MD, professor of medicine at the Rutgers New Jersey Medical School, told Verywell. Fortunately, the pinkeye observed in people with XBB.1.16 appears to run its conventional course and resolve in about a week, says Schaffner. The best way to protect yourself from any subvariant is to stay up to date on your COVID-19 vaccinations, the experts emphasize. A small January study on patients hospitalized with Omicron in Japan found that people were unlikely to shed the virus after 10 days of their diagnosis or symptom onset. But its never 100%, and it wanes over time. Learn more about the flu and how to get your flu shot from UC Davis Health. The Omicron variant is more capable of evading natural immunity, and the interval between infection and reinfection with COVID-19 may be shorter. "As your body starts recognizing the fact that it's been infected, your immune system will start taking actions, and those actions are those symptoms that you feel: fatigue, headache, malaise," Dr. Adalja said. Learn how to schedule your COVID-19 vaccine, boosters and additional doses, and the available treatments if you get COVID-19. Your previous immunity does not protect you from the latest strain. Moss says determining Omicron immunity is complex for the following reasons: High levels of antibodies likely last for four to six months after infection with Omicron, as for earlier variants, in most otherwise healthy individuals, Moss said. How long do omicron subvariant symptoms last? Parents who are concerned about the potential new XBB.1.16 symptoms should vaccinate their children, the experts note. However, the interval alone does not dictate the risk of reinfection. Others experience no symptoms at all. "It can and does occur in a small percentage of cases. Like Arcturus, XBB.1.5 is also considered a variant of interest, per the WHO, and has been circulating widely since last fall. Is my upset stomach a symptom of Omicron? Wearing a mask in these situations helps protect vulnerable people you could unknowingly infect. That means even if you were infected with delta or omicron BA.1, you can still get BA.5. A CDC study in January assessed the bivalent vaccine introduced last fall for its effectiveness against Omicron subvariants XBB and XBB.1.5 in people who had previously received two to four monovalent vaccine doses. Yes, COVID-19 vaccines continue to provide good protection against the BA.5 variant. The Omicron variant is now the dominant COVID-19 strain in the United States, with the subvariant BA.2 accounting for the majority of current cases. Does Omicron Increase COVID-19 Reinfection Risk? The Lancet. At-Home COVID-19 antigen tests-Take steps to reduce your risk of false negative: FDA safety communication. However, its still important to get vaccinated to increase the protection against infection and minimize the risk of severe outcomes from the disease. That said, the length of symptoms varies greatly depending on the person, their vaccination status, the severity the disease, and any risk factors. Centers for Disease Control and Prevention. Immunocompromised people may have a harder time clearing the infection and can therefore stay contagious longer. A handful of new siblings are being . The data suggests that . UC Davis Health is offering bivalent boosters for anyone at any of ourCOVID-19 vaccine clinic locations. doi:10.1001/jamainternmed.2021.2959, Roskosky M, Borah BF, DeJonge PM, et al. This compares to only 44 per cent of those who had Delta. MMWR Morb Mortal Wkly Rep. 2021;70:17821784. However, its important to note that they can be contagious before that, and that not everyone will develop symptoms. Even if XBB.1.16 is better at evading immunity from the vaccine, it can still provide some protection, the experts note. One caveat, Pekosz notes, is that the level of testing has decreased, and fewer cases are being sequenced compared to even just a year ago. Why this subvariant might invoke an inflammatory response in the eyes is not known, says Schaffner. By Claire Wolters We may earn commission from links on this page, but we only recommend products we back. For instance, you might want to get the immunity boost closer to an upcoming indoor event or overseas trip. Prior Omicron infection protects against BA.4 and BA.5 variants. This way, they can potentially get a prescription for Paxlovid, an antiviral medication used to help prevent severe illness from the disease. While these mutations may give XBB.1.16 an advantage in terms of its ability to spread in the population and escape immunity, says Ko, there is not enough evidence yet to know the exact severity of illness it causes. How Many Times Can You Get Reinfected With the Same COVID Variant? Delaying the shot allows eligible individuals to get the second booster when the antibody levels are likely waning. Another study on Delta and Omicron infections in the NBA found that on average, Omicron infections lasted for about 10 days, while Delta infections lasted for about 11 days. But experts have eagerly documented current and earlier Omicron-based outbreaks in major cities across the country, allowing them to have a better idea of how well vaccines are protecting individuals and influencing recovery periods in 2022. Otherwise, the symptoms of XBB.1.16 seem to be similar to those caused by other omicron variants, which include: If you or your child has any of these symptoms, the experts recommend getting tested for COVID-19. COVID-19 reinfections are generally defined as testing positive more than 90 days after the complete resolution of the primary infection. Isolation and precautions for people with COVID-19. One study found that Omicron symptoms could last anywhere from a few days to a week. It certainly seems like when symptoms go away, infectious virus disappears. Data has shown that most people who catch Omicron will recover in less than a week. National Institute of Infectious Diseases, Japan. "Breakthrough cases occur when COVID-19 variants evade the body's immune response but most breakthrough cases are asymptomatic or mild, due to the vaccinated person having built-up immunity against the virus. While a slight majority of Americans have received a full vaccination against COVID-19 sometime over the past few years the figure stands at .css-1me6ynq{-webkit-text-decoration:underline;text-decoration:underline;text-decoration-thickness:0.0625rem;text-decoration-color:#125C68;text-underline-offset:0.25rem;color:#125C68;-webkit-transition:all 0.3s ease-in-out;transition:all 0.3s ease-in-out;}.css-1me6ynq:hover{color:#595959;text-decoration-color:#595959;}around 60%, according to public data new variations of SARS-CoV-2 are proving to be more contagious than ever before. Meanwhile, loss of taste and smell, which was a common symptom with previous variants, is less likely to occur with Omicron. Omicron is surging out of control in the city, with the rolling daily average up 79% over the averages for the prior four weeks and hospitalizations up 64% by the same parameters. Omicron BA.5 is more likely to cause less severe illness compared to other variants. Omicron and its variants are better able to escape protective immunity from prior vaccination or infection compared with previous variants, Moss said. Nature. Whether or not the difference in timeframe could be attributed to characteristics of the variants themselves, or to factors like vaccinations and natural immunity was unclear, according to the researchers. Vaccines are the most protective and effective form of COVID-19 prevention available but many don't realize current vaccines aren't designed to avert COVID-19 transmission entirely, as "their strength is in preventing systemic illness and serious illness in the lungs," explains Peter F. Wright, M.D., infectious disease and international health practitioner for New Hampshire's largest academic medical system, Dartmouth Health. You can opt-out at any time. The second booster shot is available for immunocompromised individuals and people ages 50 and above who got their first booster dose at least four months ago. The research, conducted in the region of South Africa where Omicron first arose, also showed that the length of hospital stays reduced from an average of 8.8 days to an average of around four. Doctors have anecdotally observed that Artcturus, or XBB.1.16, may be causing pinkeye, or conjunctivitis, experts tell TODAY.com. That's because infectiousness declines much more quickly in immunocompetent people, according to MacDonald. How effective are N95 masks vs. surgical masks vs. cloth masks? Carla M. Delgado is a health and culture writer based in the Philippines. ), Read more about bivalent boosters from the FDA, View the California Department of Public Health's statement on bivalent vaccines. In a Nov. 22 White House . Patients who receive primary care or specialty care from UC Davis Health can schedule a telehealth video visit with Express Care. "There are additional treatment options available for vaccinated people over age 65, or those with high-risk comorbidities that experience a breakthrough COVID case," Boden-Albala adds. Researchers looked at. Omicron Variants BQ.1 and BQ.1.1 Are Now Dominant in U.S. What You Need to Know About the XBB.1.5 'Kraken' Variant. Study co-author Danny Altmann from Imperial College London told the British Medical Journal that Omicron is "an especially stealthy immune evader. Most healthy adults still have to wait. Decreasing incidence of chemosensory changes by COVID-19 variant. Omicron Variants BQ.1 and BQ.1.1 Are Now Dominant in U.S. How Long Will COVID-19 Vaccine-Induced Immunity Last? People who havelong COVID-19 symptomscan experience health problems for four or more weeks after first being infected,according to the CDC. Getting tested at the onset of these symptoms, even if you're someone who normally experiences seasonal allergies during this time of year, can enable you to shorten your recovery time. Yes. Although it can vary, people are generally contagious between 1-3 days before omicron symptoms show. pic.twitter.com/9T6YNK1kYE. It is highly contagious. U.S. Food & Drug Administration. The Japanese study showed people were most infectious with Omicron three to six days after symptom onset. What exactly is the XBB.1.16 Arcturus subvariant, how transmissible is it compared to other omicron subvariants, and which symptoms should people be looking out for? "We should all take advantage of the antigen tests that are out there," Pekosz said, noting that more at-home rapid tests are available for purchase now than there were this winter. "I would suggest that an infection that occurs after vaccination would last, on average, about four to five days, and would be accompanied by a runny nose, sore throat and cough," he adds. Experts Examine Average Recovery Timelines, Experts Reveal Common Omicron Subvariant Symptoms. According to the ZOE COVID Symptom Study, 70 per cent of patients recover from Omicron symptoms in seven days. So answers, including how sick does omicron make people and how well do vaccines hobble it, can't come fast enough. XBB.1.16 is already taking off in the the U.S. and will likely climb, says Ko, and whenever cases go up, there is a potential for COVID-19 hospitalizations and deaths to go up, as well. Despite unknowns, Pekosz said it appears reasonable to assume that once a persons Omicron symptoms go away, so has their infection. Usually, healthcare providers ask that sick individuals wait until they've recovered and no longer must quarantine to think about signing up for an additional COVID-19 vaccine but CDC officials note that some may choose to wait an additional 12 weeks from the end of their recovery. If you test positive, then you should isolate. Although the national COVID-19 public health emergency is ending soon, COVID-19 is not over, the experts note. How long before I had symptoms was I possibly contagious with omicron? The experts emphasize that we're still learning about XBB.1.16 as it continues to spread. The Omicron variant is more capable of evading natural immunity, and the interval between infection and reinfection with COVID-19 may be shorter. These include the risk of exposure to the virus based on the level of transmission in the community, the nature of the variant being transmitted, and how well it can escape prior immunity.. The most accurate way to tell if you're currently experiencing a breakthrough COVID-19 illness is to get tested. Even if masking is not required, consider wearing a mask in public indoor spaces if you or people you live with are at high risk for severe disease. The Omicron wave in the U.S. only started about six months ago, which means researchers have only had a short window to observe immunity trends. Sharma noted that, in general, symptoms appear to be shorter and milder in vaccinated people compared to unvaccinated people. The researchers found that people with no prior COVID-19 infection who then had Omicron showed enhanced immunity to previous variants but a reduced boosting against the Omicron spike protein itself. As of May 19th, over 45% of the U.S. population is in an area with a medium or high COVID-19 Community Level.At high COVID-19 Community Levels, people should be masking.At medium levels, people should consider masking based on personal risk. Updated Jan. 27, 2023 The omicron subvariant of COVID-19, BA.5, became one of the dominant strains of the virus in the fall of 2022 in the U.S. At that time, it was the most easily spread strain to date and is able to evade immunity from COVID infection and vaccination. If you test negative but continue to feel ill, you can test again 48 hours after the first negative test, for a total of at least two tests, says the Food and Drug Administration (FDA). Research published in April 2022 in The Lancet also found that sore throat and hoarse voice were consistently more prevalent with Omicron infections than with Delta. A study from the Centers for Disease Control and Prevention (CDC) identified 10 patientseight of them younger than 18 years oldwho were infected with the Delta variant and reinfected with Omicron. So, a short wait is prudent. These tests are pretty reliable, but they're not perfect. ", Updated @CDCgov data for vaccine protection from death, per 1000,000 peopleSubstantial absolute risk reduction across all 3 groups over time since peak of Omicron BA.1 wavePersistent high relative risk reduction of vaccination 87%, and with booster 92%https://t.co/HGyjNwCm0v pic.twitter.com/PCp2EPDttC. You can schedule your bivalent vaccine throughMyUCDavisHealth(non-patients without a login will have to create an account) or by calling916-703-5555. Thank you, {{form.email}}, for signing up. However, a later study reported in Nature in July 2022 suggests that, while the Omicron BA.4 and BA.5 subvariants may be stealthier at evading the immune system than all of their predecessors, a prior Omicron infection is substantially more effective to protect against reinfection than any previous COVID-19 variant. "This leaves open the opportunity for new variants that evade the vaccines to emerge, so we need to continue to vaccinate as much of the U.S. and global population as possible.". Here's what to know about the Omicron variant. Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years experience in consumer-oriented health and wellness content. "The current recommended vaccines are effective at preventing serious disease for all of the omicron variants," says Schaffner, adding that it seems like they will do the same for XBB.1.16. Studies suggest that Omicron infections can last in the body for up to 10 days. Whether changes in duration of infection are a result of variant characteristics or the public's vaccination status is unclear. Here's what you need to know. A recent study published in Science confirmed that the Omicron variant has a pronounced ability to evade immunity from prior infection, unlike the Beta or Delta variants. What can I do to protect myself and my family from omicron BA.5? For the most recent updates on COVID-19, visit ourcoronavirus news page. Editor's Note (4/18/23): On April 18 the Food and Drug Administration authorized a . Since the bivalent boosters, known as the "updated boosters" are so new, there is no effectiveness data available yet. A June 2022 study published in Science concluded that people infected with the Omicron variant show poor immunity boosting against future COVID-19 infection. How Long Do Breakthrough COVID-19 Symptoms Last? Jansen L, Tegomoh B, Lange K, et al. Its important to remember that you may be asymptomatic and not know you are infected but still able to spread COVID-19. If you've been exposed to someone with COVID-19 or are having symptoms, at-home tests can give you a good sense of whether or not you have an infection. While some people have reported 'Paxlovid rebound'or a recurrence of COVID-19 symptoms after they've finished their course of treatmentthose rebound symptoms tend to be mild and only last a few days. You should also isolate if you are sick and suspect that you have COVID-19 but do not yet have test results. 2022;376(6593):eabn4947. The bivalent booster vaccine is approved by the U.S. Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC). "If you got infected with any of the versions of Omicron there is probably good cross-protection of BA.1 and BA.2and maybe less so with BA.4 and BA.5but for the immediate period of a couple of months to several months after infection, it's unlikely that you'll get [re]infected," Dr. Adalja said. "Still, breakthrough cases are less likely to cause long-COVID.". Health.com uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Claire Wolters is a staff reporter covering health news for Verywell. However previous, studies show that bivalent vaccines result in a stronger immune response against current variants such as BA.5 and help protect against the original strain. Your recovery period (and subsequent isolation) may be lessened if you take advantage of current antiviral treatments, including the prescribed outpatient treatment Paxlovid, as well as a few other options. While Health is trying to keep our stories as up-to-date as possible, we also encourage readers to stay informed on news and recommendations for their own communities by using the CDC, WHO, and their local public health department as resources. 2022;399(10335):1618-1624. doi:10.1016/s0140-6736(22)00327-0. doi:10.1001/jamanetworkopen.2022.27241. That may influence how long youre protected. COVID Is 'Still Here': Experts Say Masking This Fall and Winter Is a Good Idea, What You Should Know About BA.2, a SARS-CoV-2 Omicron Variant, COVID-19 Boosters Are Being Updated To Target Omicron SubvariantsHere's Why, BA.2.75 Is the Newest Omicron SubvariantHere's What We Know So Far, Awareness of SARS-CoV-2 Omicron variant infection among adults with recent COVID-19 seropositivity, Investigation of a SARS-CoV-2 B.1.1.529 (Omicron) variant cluster Nebraska, NovemberDecember 2021, At-Home COVID-19 antigen tests-Take steps to reduce your risk of false negative: FDA safety communication, SARS-CoV-2 B.1.1.529 (Omicron) Variant United States, December 18, 2021, Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-COV-2 during periods of Omicron and Delta variant dominance: A prospective observational study from the ZOE COVID Study, Decreasing incidence of chemosensory changes by COVID-19 variant.